Cover [Abstract] Entity Registrant Name Entity Central Index Key Document Type Amendment Flag Entity Voluntary Filers Current Fiscal Year End Date Entity Well Known Seasoned Issuer Entity Small Business Entity Shell Company Entity Emerging Growth Company Entity Current Reporting Status Document Period End Date Entity Filer Category Document Fiscal Period Focus Document Fiscal Year Focus Entity Common Stock Shares Outstanding Entity Public Float Document Annual Report Document Transition Report Document Fin Stmt Error Correction Flag Entity File Number Entity Incorporation State Country Code Entity Tax Identification Number Entity Address Address Line 1 Entity Address Address Line 2 Entity Address City Or Town Entity Address State Or Province Entity Address Postal Zip Code City Area Code Icfr Auditor Attestation Flag Auditor Name Auditor Location Auditor Firm Id Local Phone Number Security 12b Title Trading Symbol Security Exchange Name Entity Interactive Data Current CONDENSED CONSOLIDATED BALANCE SHEETS Statement [Table] Statement [Line Items] Class of Stock [Axis] Series A Preferred Stock [Member] ASSETS Current assets Cash and cash equivalents Prepaid expenses Other current assets Total current assets [Assets, Current] Right of use asset Property and equipment, net Other assets Total assets [Assets] LIABILITIES AND STOCKHOLDERS' EQUITY Current liabilities Accounts payable Accrued liabilities Note Payable Total current liabilities [Liabilities, Current] Long term liabilities Lease liability Total long term liabilities [Liabilities, Noncurrent] Total liabilities [Liabilities] Commitments and contingencies; See Note F Stockholders' equity Preferred stock, undesignated, authorized 4,818,654 shares; See Note E Series A Preferred stock, par value $0.0001, issued 5,181,346 shares; outstanding 210, as of December 31, 2023 and December 31, 2022, respectively Common stock, par value $0.0001 per share; authorized 400,000,000 shares; issued and outstanding 298,281 as of December 31, 2023 and 28,648 as of December 31, 2022 Additional paid-in capital Accumulated deficit Total stockholders' equity [Stockholders' Equity Attributable to Parent] Total liabilities and stockholders' equity [Liabilities and Equity] Common Stock, Par Value Common Stock, Shares Authorized Common Stock, Shares Issued Common Stock, Shares Outstanding Preferred Stock, Undesignated Shares Authorized Preferred Stock, Par Value Prefered Stock, Shares Issued Prefered Stock ,Shares Outstanding CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS Operating expenses General and administrative Research and development Total operating expenses [Operating Expenses] Net operating loss Interest expense Other income, net Net loss [Net Income (Loss) Attributable to Parent] Total comprehensive loss [Comprehensive Income (Loss), Net of Tax, Attributable to Parent] Net loss per share, basic and diluted Weighted average number of common shares outstanding, basic and diluted CONSOLIDATED STATEMENTS OF STOCKHOLDERS EQUITY Equity Components [Axis] Preferred Stock Common Stock Additional Paid-In Capital Accumulated Deficit Balance, shares [Shares, Issued] Balance, amount Pre-funded warrants and warrants sold, net of offering costs Exercise of pre-funded warrants, shares Exercise of pre-funded warrants, amount Compensation on options issued Net loss [Net loss] Public offering sale of common stock and warrants, shares Public offering sale of common stock and warrants, amount Exercise of pre-funded warrants for cash, shares Exercise of pre-funded warrants for cash, amount Exercise of pre-funded warrants, cashless, shares Exercise of pre-funded warrants, cashless, amount Exercise of warrants, cashless, shares Exercise of warrants, cashless, amount Stock split and fractional shares issued, shares Stock split and fractional shares issued, amount Balance, shares Balance, amount CONSOLIDATED STATEMENTS OF CASH FLOWS CASH FLOWS FROM OPERATING ACTIVITIES Net Loss Adjustments to reconcile net loss to net cash used in operating activities Depreciation and amortization Interest on debt instrument Amortization of right of use asset (Gain)/Loss on sale of equipment [Gain (Loss) on Disposition of Property Plant Equipment] Issuance and vesting of compensatory stock options and warrants Changes in operating assets and liabilities Accounts receivable, prepaid expenses and other assets [Increase (Decrease) in Accounts Receivable and Other Operating Assets] Accounts payable and accrued liabilities Long term portion of lease liability Net cash used in operating activities [Net Cash Provided by (Used in) Operating Activities] CASH FLOWS FROM INVESTING ACTIVITIES Proceeds from sale/(purchase) of property and equipment Net cash (used in) provided by investing activities [Net Cash Provided by (Used in) Investing Activities] CASH FLOWS FROM FINANCING ACTIVITIES Proceeds from issuance of warrants and pre-funded warrants, net of issuance costs Proceeds from the exercise of warrants Payments on short-term note [Repayments of Notes Payable] Net cash provided by financing activities [Net Cash Provided by (Used in) Financing Activities] Net change in cash and cash equivalents [Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Excluding Exchange Rate Effect] Cash and cash equivalents, beginning of period Cash and cash equivalents, end of period Non-cash operating activity Addition to prepaids for insurance premium Non-cash financing activity Addition to notes payable for financing insurance premium DESCRIPTION OF BUSINESS DESCRIPTION OF BUSINESS Business Description and Basis of Presentation [Text Block] SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES Significant Accounting Policies [Text Block] BALANCE SHEET COMPONENTS BALANCE SHEET COMPONENTS Supplemental Balance Sheet Disclosures [Text Block] NOTE PAYABLE NOTE PAYABLE Debt Disclosure [Text Block] STOCKHOLDERS EQUITY STOCKHOLDERS' EQUITY COMMITMENTS AND CONTINGENCIES Commitments and Contingencies Disclosure [Text Block] BENEFIT PLAN BENEFIT PLAN Schedule of Defined Benefit Plans Disclosures [Table Text Block] INCOME TAXES INCOME TAXES Income Tax Disclosure [Text Block] SUBSEQUENT EVENTS SUBSEQUENT EVENTS Subsequent Events [Text Block] Use Of Estimates Principles Of Consolidation Reverse Stock Split Cash And Cash Equivalents Cash Concentration Risk Liquidity And Capital Resources Stock-Based Compensation Loss Per Share Recent Accounting Pronouncements Fair Value Reclassification of Prior Year Presentation Operating Leases Income Taxes Research and Development Costs Property and Equipment, Net Preclinical Study and Clinical Accruals Anti-dilutive Securities Accrued Liabilities Plan Name Axis 2016 Plan Stock Options 2022 Plan Stock Options 2022 Stock Incentive Plan 1999 Plan Stock Options Schedule of Warrants Activity Summary of vest based option outstanding Schedule of options outstanding Schedule of Black-Scholes Option Pricing model Summarizes shares available for grant Schedule of outstanding stock options Accumulated Deficit [Cumulative Earnings (Deficit)] Cash Used In Operating Activities Class of Warrant or Right [Axis] Options To Purchase Common Stock[Member] Warrants To Purchase Common Stock[Member] Pre-Funded Warrants To Purchase Common Stock [Member] Covertible Preferred Shares Outstanding [Member] Anti- Securities Dilutive Related Party [Axis] Intra Fi Network [Member] Cash uninsured amount Federal Deposit Insurance Corporation insurance limits Total current assets [Capital Lease Obligations, Current] Working capital amount Cash resources Non-cash expense Operating Costs Lease Liability Employee Related Total [Accounts Payable and Accrued Liabilities, Current] Depreciation expense Note Payable Proceeds from issuance of note payable Interest rate on notes payable Note payable downpayment Monthly installment Warrants outstanding beginning [Class of Warrant or Right, Outstanding] Warrants issued Warrants amended and restated Warrants amended and restated [Warrants amended and restated] Exercised Canceled Warrants outstanding ending Warrants,Weighted average exercise price beginning [Class of Warrant or Right, Exercise Price of Warrants or Rights] Weighted average exercise price, issued Weighted average exercise price, Amended and restated Weighted average exercise price, Amended and restated [Weighted average exercise price, Amended and restated] Weighted average exercise price, excercised Weighted average exercise price, Canceled Warrants, weighted average exercise price, ending Remaining contractual term Risk free interest rate Expected dividends Expected Volatility Measurement Input Type [Axis] Exercise Price One [Member] Exercise Price Two [Member] Exercise Price Three [Member] Exercise Price Four [Member] Weighted average remaining contractual life Number of options exercisable and vested Options exercisable and vested weighted average exercise price Exercise Price Number of options outstanding Stock Options [Member] Number of option shares vested Weighted average exercise price vested Aggregate intrinsic value vested Weighted average remaining contractual life vested Number of option shares vested and expected to vest Weighted average exercise price vested and expected to vest Aggregate intrinsic value vested and expected to vest Weighted average remaining contractual life vested and expected to vest Grant under 2022 Plan Options granted, beginning Shares reserved under 2022 Plan Shares rolled over from 2016 Plan Options Granted Options cancelled/forfeited Options granted, ending Number of shares, Options Outstanding, Beginning Number of shares, Options Outstanding, Options granted Number of shares, Options Outstanding, cancelled/forfeited [Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period] Number of shares, Options Outstanding, Ending Weighted average exercise price, option outstanding, Beginning Balance [Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price] Weighted average exercise price, Options Options granted Weighted average exercise price, Options cancelled/forfeited Weighted average exercise price, option outstanding, Ending Balance Grant under 2016 Plan [Member] Warrants,Weighted average exercise price, Options cancelled/forfeited Risk-free interest rate (weighted average) Expected volatility (weighted average) Expected term (in years) Expected dividend yield Stock Options 1999 Plan [Member] Number of shares, Options Outstanding Options cancelled [Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Expirations in Period] Warrants,Weighted average exercise price, Options cancelled Aggregate intrinsic value, option outstanding Award Date Axis Award Type Axis Series A Stock Plan Febuary 2023 Offering Febuary 2023 May 2022 Offering [Member] Pre-Funded Warrants [Member] May 2022 Warrants Inducement Stock Options [Member] Chief Medical Officer [Member] First Inducement Stock Options Second Inducement Stock Options 1999 Amended Stock Plan 2016 Stock Incentive Plan Warrants July 2020 Offering [Member] February 2023 Offering [Member] Underwritten offering Exercise price Common Stock, Shares Authorized Common Stock, Par Value Common Stock, Shares Outstanding Warrant To Purchase Of Unregistered Common Stock Common stock shares Warrnat purchase Offering Price Common stock warrant Gross proceeds form warrant Agent fees and direct offering expenses fair value allocated Pre-funded Warrants, Fair Value Pre-funded warrants Warrant Estimated fair value Stock issued during period, shares Proceeds From Issuance Of Private Placement Warrants outstanding ending Warrant To Purchase Of Unregistered Common Stock, Value Share issued Pre-funded warrants issued Number Of Shares Of Common Stock Authorized For Issuance Unrecognized Compensation Costs Weighted average remaining vesting period Number Of Shares Previously Authorized For Issuance Stock Options Granted, Vesting Period Compensation Expense Stock Option Award Granted Stock Options Description Estimated Fair Value Of The Inducement Stock Option Award Granted Risk-free interest rate Dividend Yield Volatility Factor Rate Expected Life Current Portion Included In Accrued Liabilities Long Term Lease Liability Total [Operating Lease, Liability] Simdax License Agreement [Member] Annual Lease Term minimum Annual Lease Term maximum Grant paid to canadian authority Grant paid to authority Non refundable up front payment Non-refundable commercialization milestone payment Lease Term Period Optioin to extend description Current rent Annual Base Rent Increased Percentage Of Annual Increase In Rent 401(k) BENEFIT PLAN (Details Narrative) 401(k) Retirement Savings Plan [Member] Contribution Term Period Contributions expense Contribution percentage rate U.S. federal tax benefit at statutory rate [Effective Income Tax Rate Reconciliation at Federal Statutory Income Tax Rate, Amount] State income tax benefit, net of federal benefit [Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Amount] Stock compensation Other nondeductible Change in state tax rate Expiration of NOL Carryforward Federal and state net operating loss adjustments Other, including effect of tax rate brackets Change in realizability of IPR and D Change in valuation allowance Deferred Tax Assets Net operating loss carryforwards Accruals and others Capitalized R&D Contributions carryforwards Valuation allowance [Deferred Tax Assets, Valuation Allowance] Net deferred tax assets Deferred Tax Liabilities Other liabilities [Deferred Tax Liabilities, Other] Net deferred tax liabilities Income Tax Authority Axis Federal [Member] State [Member] Income tax rate Description of income taxes Valuation allowance, decrease Description for Operating Loss Carryforwards Operating Loss Carryforwards Net operating losses Remaining operating losses carryforward Subsequent Event Type [Axis] Related Party Transaction [Axis] Subsequent Events [Member] Roth Capital Partners, LLC [Member] Sale of common stock shares Minimum public shares Share description Common stock, minimum closing price per share Levosimendan-based product Milestone payment Aggregate milestone payment Sale of common stock, price per share Issuance of pre fund warrant shares Warrants to purchase shares of common stock Issuance of pre fund warrant shares, offering price per share Common warrant, pre-funded warrant per share price Gross proceeds from common stock warrants Estimated net proceeds from public offering after deduction of placement agent fees and estimated offering expenses payable Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element.