Cover [Abstract] Entity Registrant Name Entity Central Index Key Document Type Amendment Flag Entity Voluntary Filers Current Fiscal Year End Date Entity Well Known Seasoned Issuer Entity Small Business Entity Shell Company Entity Emerging Growth Company Entity Current Reporting Status Document Period End Date Entity Filer Category Document Fiscal Period Focus Document Fiscal Year Focus Entity Common Stock Shares Outstanding Entity Public Float Document Annual Report Document Transition Report Entity Interactive Data Current Entity File Number Entity Incorporation State Country Code Entity Tax Identification Number Entity Address Address Line 1 Entity Address Address Line 2 Entity Address City Or Town Entity Address State Or Province Entity Address Postal Zip Code City Area Code Local Phone Number Security 12b Title Trading Symbol Security Exchange Name Icfr Auditor Attestation Flag Auditor Name Auditor Location Auditor Firm Id CONDENSED CONSOLIDATED BALANCE SHEETS ASSETS Current assets Cash and cash equivalents Prepaid expenses Marketable securities Total current assets [Assets, Current] Right of use asset Property and equipment, net Other assets Total assets [Assets] LIABILITIES AND STOCKHOLDERS' EQUITY Current liabilities Accounts payable Accrued liabilities Note payable Total current liabilities [Liabilities, Current] Long term liabilities Lease liability Note payable [Notes Payable] Total long term liabilities [Liabilities, Noncurrent] Total liabilities [Liabilities] Commitments and contingencies; see Note G Stockholders' equity Preferred stock, undesignated, authorized 4,818,654 shares; See Note F Series A Preferred stock, par value $.0001, issued 5,181,346 shares; outstanding 210, respectively Common stock, par value $.0001 per share; authorized 400,000,000 shares; issued and outstanding 25,206,914 and 12,619,369, respectively Additional paid-in capital Accumulated other comprehensive loss Accumulated deficit Total stockholders equity [Stockholders' Equity Attributable to Parent] Total liabilities and stockholders' equity [Liabilities and Equity] Statement [Table] Statement [Line Items] Statement Class Of Stock Axis Series A Preferred Stock Stockholders' equity Preferred stock, shares authorized Common stock, par value Common stock, shares authorized Common stock, shares issued Common stock, shares outstanding Preferred stock, par value Preferred stock, shares issued Preferred stock, shares outstanding CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS Operating expenses General and administrative Research and development Total operating expenses [Operating Expenses] Net operating loss Interest expense Other income, net Net loss [Net Income (Loss) Attributable to Parent] Unrealized (gain)/loss on marketable securities Total comprehensive loss [Comprehensive Income (Loss), Net of Tax, Attributable to Parent] Net loss per share, basic and diluted Weighted average number of common shares outstanding, basic and diluted CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS EQUITY Statement Equity Components [Axis] Preferred Stock Common Stock Additional Paid-In Capital Accumulated Other Comprehensive Gain (Loss) Accumulated Deficit Balance, shares [Shares, Issued] Balance, amount Common stock and pre-funded warrants sold, net of offering costs, shares Common stock and pre-funded warrants sold, net of offering costs, amount Common stock issued for services rendered, shares Common stock issued for services rendered, amount Common stock issued for convertible preferred stock, shares Common stock issued for convertible preferred stock, amount Exercise of pre-funded warrants, shares Exercise of pre-funded warrants, amount Exercise of warrants, shares Exercise of warrants, amount Compensation on options issued Unrealized loss on marketable securities Net loss Common stock and preferred stock issued for asset acquisition, shares Common stock and preferred stock issued for asset acquisition, amount Pre-funded warrants sold, net of offering costs Exercise of stock options, shares Exercise of stock options, amount Balance, shares Balance, amount CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS CASH FLOWS FROM OPERATING ACTIVITIES Net Loss [Net Income (Loss), Including Portion Attributable to Noncontrolling Interest] Adjustments to reconcile net loss to net cash used in operating activities Depreciation and amortization Interest on debt instrument [Increase (Decrease) in Interest and Dividends Receivable] Amortization of right of use asset Gain on debt settlement and extinguishment [Gain (Loss) on Extinguishment of Debt] Issuance and vesting of compensatory stock options and warrants Issuance of common stock and preferred stock for asset acquisition Issuance of common stock for services rendered Amortization of premium on marketable securities Changes in operating assets and liabilities Accounts receivable, prepaid expenses and other assets [Increase (Decrease) in Prepaid Expense and Other Assets] Accounts payable and accrued liabilities Long term portion of lease liability Net cash used in operating activities [Net Cash Provided by (Used in) Operating Activities] CASH FLOWS FROM INVESTING ACTIVITIES Sale of marketable securities Purchase of marketable securities [Payments to Acquire Marketable Securities] Purchase of property and equipment [Payments to Acquire Property, Plant, and Equipment] Net cash provided by investing activities [Net Cash Provided by (Used in) Investing Activities] CASH FLOWS FROM FINANCING ACTIVITIES Proceeds from issuance of common stock and pre-funded warrants, net of issuance costs Proceeds from the exercise of warrants Proceeds from the issuance of notes payable Net cash provided by financing activities [Net Cash Provided by (Used in) Financing Activities] Net change in cash and cash equivalents [Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Excluding Exchange Rate Effect] Cash and cash equivalents, beginning of period [Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents] Cash and cash equivalents, end of period Non-cash investing activity Addition to right of use asset obtained from new operating lease liability DESCRIPTION OF BUSINESS DESCRIPTION OF BUSINESS Business Description and Basis of Presentation [Text Block] SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES Significant Accounting Policies [Text Block] BALANCE SHEET COMPONENTS BALANCE SHEET COMPONENTS Supplemental Balance Sheet Disclosures [Text Block] NOTES PAYABLE NOTE PAYABLE MERGER MERGER Mergers, Acquisitions and Dispositions Disclosures [Text Block] STOCKHOLDERS' EQUITY 401(k) BENEFIT PLAN 401(k) BENEFIT PLAN Compensation and Employee Benefit Plans [Text Block] COMMITMENTS AND CONTINGENCIES COMMITMENTS AND CONTINGENCIES Commitments and Contingencies Disclosure [Text Block] INCOME TAXES INCOME TAXES Income Tax Disclosure [Text Block] SUBSEQUENT EVENTS SUBSEQUENT EVENTS Subsequent Events [Text Block] Use of Estimates Principles of Consolidation Cash and Cash Equivalents Cash Concentration Risk Liquidity and Capital Resources Deferred Financing Costs Derivative Financial Instruments Preclinical Study and Clinical Accruals Property and Equipment, Net Research and Development Costs Income Taxes Stock-Based Compensation Loss Per Share Operating Leases Recent Accounting Pronouncements Fair Value Investments in Marketable Securities Anti-dilutive securities Fair value measurements Accrued liabilities Schedule of Accrued Liabilities [Table Text Block] Consideration transferred, asset acquired and liabilities assumed STOCKHOLDERS' EQUITY (Tables) Warrant activity Outstanding stock options Options vested and expected to vest Shares available for grant under the Plan Stock options activity Fair value assumptions Outstanding stock options under the 1999 plan Lease liability Lessee, Operating Leases [Text Block] Operating lease liability maturity Reconciliation of income tax expense (benefit) Deferred tax assets and liabilities Accumulated deficit Net cash used in operating activities Class of Warrant or Right [Axis] Warrants To Purchase Common Stock[Member] Options To Purchase Common Stock[Member] Covertible Preferred Shares Outstanding [Member] Pre-Funded Warrants To Purchase Common Stock [Member] Anti- securities dilutive Fair Value Hierarchy and NAV [Axis] Fair Value Inputs Level 1 [Member] Fair Value Inputs Level 2 [Member] Fair Value Inputs Level 3 [Member] Current Assets Cash and cash equivalents [Cash and Cash Equivalents, Fair Value Disclosure] Marketable securities [Available-for-sale Securities] Uninsured FDIC Current assets Working capital Cash Employee related Lease liability [Operating Lease, Liability, Current] Operating costs Total Depreciation and amortization expense PPP loan amount Accrued interest PPP loan - principal payable Fair value of shares of Common Stock issued Fair Value of Series B Convertible Preferred Stock issued at closing Total fair value of consideration transferred Tangible assets acquired Accounts payable assumed [Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Current Liabilities, Accounts Payable] Total identifiable net assets IPR&D expense recognized Total fair value of consideration Common stock acquired Stock issued for conversion Percentage of Preferred Stock carries voting rights Number of warrants outstanding, beginning [Share-based Compensation Arrangement by Share-based Payment Award, Non-Option Equity Instruments, Outstanding, Number] Number of warrants, issued Number of warrants, exercised [Share-based Compensation Arrangement by Share-based Payment Award, Non-Option Equity Instruments, Exercised] Number of warrants outstanding, ending Number of warrants, expired [Share-based Compensation Arrangement by Share-based Payment Award, Non-Option Equity Instruments, Forfeitures] Weighted average exercise price outstanding, beginning [Class of Warrant or Right, Exercise Price of Warrants or Rights] Weighted average exercise price, issued Weighted average exercise price, exercised Weighted average exercise price outstanding, ending Weighted average exercise price, expired Exercise Price Range [Axis] Exercise Price One [Member] Exercise Price Two [Member] Exercise Price Three [Member] Exercise Price Four [Member] Number of options outstanding Weighted average remaining contractual life Number of options exercisable and vested Options exercisable and vested weighted average exercise price Number of option shares vested Weighted average exercise price vested Aggregate intrinsic value vested Weighted average remaining contractual life vested Number of option shares vested and expected to vest Weighted average exercise price vested and expected to vest Aggregate intrinsic value vested and expected to vest Weighted average remaining contractual life vested and expected to vest Plan Name [Axis] Stock Incentive Plan Two Thousands Sixteen [Member] Shares available for grant, beginning [Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant] Shares available for grant, additional shares reserved Shares available for grant, options granted [Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross] Shares avialable for grant, options forfeited Shares available for grant, ending Number of options outstanding, beginning Number of options granted Number of options exercised [Number of options exercised] Number of options cancelled/forfeited Number of options outstanding, ending Weighted average exercise price outstanding, beginning [Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price] Weighted average exercise price granted Weighted average exercise price exercised Weighted average exercise price cancelled/forfeited Weighted average exercise price outstanding, ending Aggregate intrinsic value, outstanding Expected dividend yield Expected term (in years) Expected volatility (weighted average) Risk-free interest rate (weighted average) Vesting [Axis] Amended Nineteen Ninty Nine Stock Plan [Member] Weighted average exercise price cancelled/forfeited Aggregate intrinsic value, outstanding Award Date Axis Pre-Funded Warrants Two-Year Warrant Five-Year Warrant July 2020 Offering Warrants [Member] July 2021 Offering July 2020 Warrants July 2021 Warrants March 2020 Warrants [Member] March 2020 Offerings December 2018 Offering Second Inducement Stock Options First Inducement Stock Options Inducement Stock Options Series B Preferred Stock 2016 Stock Incentive Plan 1999 Amended Stock Plan Common stock, shares authorized Common stock, par value Common stock, shares issued Common stock, shares outstanding Warrant to purchase of common stock Conversion of preferred stock into common stock, maximum ownership limit, percentage Warrants, outstanding Number of units, issued Proceeds from issuance or sale of equity Preferred stock, dividends Preferred stock, convertible, conversion price Preferred stock, par value Preferred stock, shares outstanding Warrants, exercise price Purchase price per unit Warrant to purchase of unregistered common stock Warrant to purchase of unregistered common stock, value Number of units issued Net proceeds from the offerings, after deducting placement agent fees and other direct offering expenses Fair value allocated pre-funded warrants Fair value allocated common stock Fair value allocated warrants Warrant to purchase of common stock exercise price Estimated fair value Number of securities called by Warrants Proceeds from issuance of private placement Pre-funded warrants, fair value Warrants, fair value Unregistered common stock warrants to purchase common stock [Unregistered common stock warrants to purchase common stock] Issued underwriter warrant to purchase common stock Estimated fair value of warrant issued for services Underwriter warrant to purchase common stock exercise price Unregistered common stock warrants to purchase common stock Unregistered warrants exercise price Fair value of warrants Warrant to purchase of common stock term Stock issued during period, value Stock issued during period, shares Stock options description Stock option award granted Stock options exercise term Stock options exercise price Risk-free interest rate Dividend yield Vvolatility factor rate Expected life Estimated fair value of the inducement stock option award granted Compensation expense Unrecognized compensation costs Preferred stock, shares issued Preferred stock, convertible, terms Stock convertible into an aggregate shares of common stock Number of shares authorized Number of shares previously authorized for issuance Number of shares of common stock authorized for issuance Stock options granted, vesting period Weighted average remaining vesting period Weighted average fair value Unvested shares underlying outstanding stock awards Outstanding stock awards General and administrative compensation expense Stock options granted fair market value percentage Current portion included in accrued liabilities Long term lease liability Total [Operating Lease, Liability] 2022 2023 2024 Total lease payments Less: imputed interest [Lessee, Operating Lease, Liability, Undiscounted Excess Amount] Operating lease liability Simdax License Agreement [Member] Lease term Optioin to extend description Option to terminate description Annual base rent increase Base rent increase percentage Licence term period Grant paid to canadian authority Grant paid to authority Non refundable up front payment Non-refundable commercialization milestone payment Matching contributions expense for retirement savings plan U.S. federal tax benefit at statutory rate [Effective Income Tax Rate Reconciliation at Federal Statutory Income Tax Rate, Amount] State income tax benefit, net of federal benefit [Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Amount] Stock compensation Other nondeductible, including IPR and D expense Change in state tax rate Federal and state net operating loss adjustments Other, including effect of tax rate brackets Change in valuation allowance Change in realizability of IPR and D Income-tax expense (benefit) Deferred Tax Assets Net operating loss carryforwards Accruals and others Capital loss carryoforwards Valuation allowance [Deferred Tax Assets, Valuation Allowance] Net deferred tax assets Deferred Tax Liabilities Other liabilities [Deferred Tax Liabilities, Other] Net deferred tax liabilities Income Tax Authority [Axis] Federal [Member] State [Member] Income tax rate Description of income taxes Valuation allowance, decrease Operating Loss Carryforwards Net operating losses Patent expiry date, description Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Custom Element. Exercise price per share or per unit of warrants or rights outstanding. Net proceeds from the offerings, after deducting placement agent fees and other direct offering expenses. Stock options description. Unregistered common stock warrants to purchase common stock. Unregistered warrants exercise price. Warrant to purchase of common stock term. Estimated fair valueof warrant issued for services. Issued underwriter warrant to purchase common stock. Underwriter warrant to purchase common stock exercise price. Stock options granted, vesting period Custom Element. Custom Element.